Phosphopeptides

Phosphopeptides are important for investigating the influence of phosphorylation on the structures of peptides and proteins and in understanding the regulatory process mediated by protein kinases. Utilizing our optimized Fmoc and Boc methodologies, we have successfully synthesized numerous serine-, threonine-, and tyrosine-phosphopeptides. For peptides containing one or more of these hydroxy amino acids, selective phosphorylation can be achieved by orthogonal protection strategy or by using Fmoc-protected phosphorylated amino acids produced in-house.

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