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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  AMCA-X, SE

Product Name AMCA - X, SE
6 - ((7 - Amino - 4 - methylcoumarin - 3 - acetyl)amino)hexanoic acid, succinimidyl ester; AMCA - X, NHS ester
Size 10 mg
Catalog # AS-81208
US$ $121
Description

AMCA-X, SE is one of the most popular blue fluorescent tagging molecules. It is widely used to label antibodies, proteins and small drug molecules. AMCA-X succinimidyl ester contains a seven-atom aminohexanoyl spacer, the so-called X spacer, between the fluorophore and the reactive group. It is well known that the spacer between the fluorophore and the reactive group usually separates the fluorophore from the biomolecule to which it is conjugated, potentially reducing the quenching that typically occurs upon conjugation. In some cases, the X spacer allows the dye to be more available for recognition by secondary detection reagents.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References Malicka J, et al. (2003). Increased resonance energy transfer between fluorophores bound to DNA in proximity to metallic silver particles. Anal Biochem 315, 160-9; Aubry JP, et al. (1990). 7-amino-4-methylcoumarin-3-acetic acid-conjugated streptavidin permits simultaneous flow cytometry analysis of either three cell surface antigens or one cell surface antigen as a function of RNA and DNA content. J Immunol Methods 128, 39-49.
Molecular Weight 443.46
Spectral Properties Abs/Em = 353/442 nm
Solvent System DMF or DMSO
     
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