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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  Tetramethylrhodamine-5-(and-6)-maleimide

Product Name Tetramethylrhodamine - 5 - (and - 6) - maleimide
Size 25 mg
Catalog # 81444
US$ $247
Description

Maleimides are among the most frequently used reagents for thiol modification. In most proteins, the sites of reactions are at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Tetramethylrhodamine-5-(and-6)-maleimide is an excellent reagent for thiol modifications of peptides, nucleotides, nucleic acids and proteins.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References Geibel S, et al. (2003). Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci USA 100, 964-9; Cha A and Bezanilla F (1998). Structural implications of fluorescence quenching in the Shaker K+ channel. J Gen Physiol 112, 391-408.
Molecular Weight 481.51
Spectral Properties Abs/Em = 540/567 nm
Solvent System DMF or DMSO
Product Citations Blanco-Canosa, J. et al. (2010). Rapid Covalent Ligation of Fluorescent Peptides to Water Solubilized Quantum Dots. J Am Chem Soc 132, 10027.
Parker, LL. et al. (2006). Photocleavable peptide hydrogel arrays for MALDI-TOF analysis of kinase activity.Analyst 131, 1097.
     
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