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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  5-TMRIA

Product Name 5 - TMRIA
5 - TAMRIA; Tetramethylrhodamine - 5 - iodoacetamide
Size 5 mg
Catalog # AS-81410
US$ $247
Description

Tetramethylrhodamine iodoacetamides (TMRIA) are thiol-selective reactive dyes that are used to label proteins via the cysteine residues. 5-TMRIA, the pure 5-isomer of TMRIA, is increasingly preferred for some particular applications since the mixed isomers of TMRIA may give different results from batch to batch due to the varying ratios and different reactivities of the two isomers. For example, 5-TAMRA is reported to predominantly label SH-1 (Cys-707) of the myosin heavy chain in skinned muscle fibers.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References Martyn DA, et al. (2001). Ca2+- and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle. Biophys J 80, 360-70; Ajtai K and Burghardt TP (1995). Conformation of xanthene dyes in the sulfhydryl 1 binding site of myosin. 2. Biochemistry 34, 15943-52.
Molecular Weight 569.39
Spectral Properties Abs/Em = 541/567 nm
Solvent System DMF or DMSO
     
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