(Z - AR)2Rh110•2HCl [Rhodamine 110, bis - (CBZ - L - alanyl - L - arginine amide)]
(Z-Ala-Arg)2Rh110 is a sensitive fluorogenic substrate for elastase and trypsin. The colorless and nonfluorescent (Z-Ala-Arg)2Rh110 is hydrolyzed to highly fluorescent rhodamine 110, which exhibits excellent spectral properties that match the optimal detection window of most fluorescence instruments.
Minimum Purity: 95%
-20°C desiccated and protected from light
Devi S, et al. (1995). Biologic activities of the beta-chemokine TCA3 on neutrophils and macrophages. J Immunol 154, 5376-83, Leytus SP, et al. (1983). New class of sensitive and selective fluorogenic substrates for serine proteinases. Amino acid and dipeptide derivatives of rhodamine. Biochem J 215, 253-60.