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Assay Kits  >  MMP Assay Kits  >>  SensoLyte® 490 MMP-2 Assay Kit *Fluorimetric*

Product Name SensoLyte® 490 MMP - 2 Assay Kit *Fluorimetric*
Size 1 kit
Catalog # 71129
US$ $601
Description

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion is well known. MMP-2 (gelatinase A) is proposed as a potential therapeutic target. The SensoLyte® 490 MMP-2 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-2 inhibitors by using a fluorogenic MMP-2 substrate. The assays are performed in a convenient 96-well or 384-well microplate format. The kit provides speed, convenience and accuracy in analyzing MMP-2 activities and in screening MMP-2 inhibitors.

Kit size: 500 assays

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Brochure
Storage -20°C
Product Citations Mei, ML. et al. (2012). The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases. Dental Mat 28, 903.
Chou, W. et al. (2010). Structure–function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells. Toxicon 55, 353.
Djouad, F. et al. (2009). ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage.Tissue Eng. doi:10.1089/ten.tea.2008.0663.
Mu, H. et al. (2008). Chlorotyrosine promotes human aortic smooth muscle cell migration through increasing superoxide anion production and ERK1/2 activation.Atheroclerosis 201, 67.
     
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