Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Assay Kits  >  MMP Assay Kits  >>  SensoLyte® 490 MMP-9 Assay Kit *Fluorimetric*

Product Name SensoLyte® 490 MMP - 9 Assay Kit *Fluorimetric*
Size 1 kit
Catalog # AS-71134
US$ $601
Description

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. MMP-9 (gelatinase-B, collagenase-IV) is involved in quite a few diseases such as a cancer, angiogenesis, alopecia and metastasis. The SensoLyte® 490 MMP-9 Assay Kit is a complete assay system designed to continuously analyze MMP activity or to screen for MMP-9 inhibitors using a fluorogenic MMP-9 substrate. The assays are performed in a convenient 96-well or 384-well microplate format. The kit provides speed, convenience and accuracy in MMP-9 analysis. Members of the MMP family have poor substrate sequence specificity, making it difficult to use a peptide substrate alone to differentiate the activity of a particular MMP from other MMPs. If several MMPs are coexisting in your samples and you would like to specifically measure MMP-9 activity, please choose the SensoLyte® Plus MMP-9 Assay Kit, Cat# 72017.

Kit size: 500 assays

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Brochure
Storage -20°C
Product Citations Won, S. et al. (2013). Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF–MMP pathway. J Cerebral Blood Flow Metabolism. doi: 10.1038/jcbfm.2013.163.
Mei, ML. et al. (2012). The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases. Dental Mat 28, 903.
Djouad, F. et al. (2009). ERK1/2 Activation Induced by Inflammatory Cytokines Compromises Effective Host Tissue Integration of Engineered Cartilage. Tissue Eng Part A 15, 2825.
Oh, JH. et al. (2009). Syndecan-1 enhances the endometrial cancer invasion by modulating matrix metalloproteinase-9 expression through nuclear factor kappaB. Gynecol Oncol 114, 509.
Lin, C. et al. (2008). Quercetin inhibition of tumor invasion via suppressing PKCδ/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma. Carcinogenesis 29, 1807.
     
  < Back