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Peptides  >  Gastrins  >>  Gastrin-1, rat

Product Name Gastrin - 1, rat
Size 1 mg
Catalog # AS-20752
US$ $127
Purity % Peak Area By HPLC ≥ 95%

Like human Gastrin-1 “Little Gastrin,” rat Gastrin-1 “Little Gastrin” contains 17 amino acids, but differs from human Gastrin by 3 amino acids at the C-terminus. Secretion of Gastrin is induced by food intake and causes the release of gastric acid. Synthesized by the G cells in the gastric mucosa, it is one of the major bioactive forms of Gastrin (the other bioactive form is Gastrin-34). Both Gastrin-17 and Gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of Gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C
References Reeve, JR. et al. Peptides 2, 453 (1981)
Schaffer, MH. et al. Peptides 3, 693 (1982), doi: 10.1016/0196-9781(82)90172-3
Niederle, B. Wien Klin Wochenschr 119, 561 (2007), doi: 10.1007/s00508-007-0897-x.
O’Connor A. et. al. Digestive Dis 32, 186 (2014), doi: 10.1159/000357848
Dockray, G. et.al. Pflügers Archiv 449,344 (2005)
Bundgaard, JR. et al. J Biol Chem 272, 21700 (1997), doi: 10.1074/jbc.272.35.21700
Yakabi, K. et al. World J Gastroenterol 14, 6334 (2008), doi: 10.3748/wjg.14.6334
Molecular Weight 2126.3
(One-Letter Code)
(Three-Letter Code)
Pyr - Arg - Pro - Pro - Met - Glu - Glu - Glu - Glu - Glu - Ala - Tyr - Gly - Trp - Met - Asp - Phe - NH2
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