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Peptides  >  Amyloid Peptides  >  Beta-Amyloid (1-42) and Related Peptides  >>  Beta-Amyloid (1-42) HCl, Human

Product Name Beta - Amyloid (1 - 42) HCl, Human
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA HCl
Size 1 mg
Catalog # AS-21793
US$ $423
Purity % Peak Area By HPLC ≥ 95%
Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
Molecular Weight 4514.136.5
Sequence
(One-Letter Code)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA HCl
Sequence
(Three-Letter Code)
H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH HCl
Product Citations Iwasaki, K. et al. (2007). Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with β-amyloid in rats. Biol Pharm Bull 30, 698.
Iwasaki, K. et al. (2006). Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats. Brain Res 1097, 216.
Hirata, K. et al. (2005). A novel neurotrophic agent, T-817MA [1-{3-[2-(1-Benzothiophen-5-yl) Ethoxy] Propyl}-3-azetidinol Maleate], attenuates amyloid-β-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. JPET 314, 252.
Iwasaki, K. et al. (2004). Ovariectomy combined with amyloid beta(1-42) impairs memory by decreasing acetylcholine release and alpha 7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats. Neurotox Res 6, 299.
Kubo, T. et al. (2003). 6-Ethyl-N,N'-bis(3-hydroxyphenyl)[1,3,5]triazine-2,4-diamine (RS-0466) enhances the protective effect of brain-derived neurotrophic factor on amyloid beta-induced cytotoxicity in cortical neurones. Pharmacol Toxicol 93, 264.
Kakimura, JI. et al. (2002). Microglial activation and amyloid-β clearance induced by exogenous heat-shock proteins. FASEB J 10.1096/fj.01-0530fje.
Nakagami, Y. et al. (2002). A novel compound RS-0466 reverses β-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro. Eur J Pharmacol 457, 11.
Nakagami, Y. et al. (2002). Glutamate exacerbates amyloid β1-42-induced impairment of long-term potentiation in rat hippocampal slices. Jpn J Pharmacol 88, 223.
Nakagami, Y. et al. (2002). A novel β-sheet breaker, RS-0406, reverses amyloid β-induced cytotoxicity and impairment of long-term potentiation in vitro. Br J Pharmacol 137, 676.
     
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