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Peptides  >  Amyloid Peptides  >  Beta-Amyloid (1-42) and Related Peptides  >>  [Pyr11]-beta-Amyloid (11-42)

Product Name [Pyr11] - beta - Amyloid (11 - 42)
Size 1 mg
Catalog # 29903-1
US$ $484
Purity % Peak Area By HPLC ≥ 95%
Description

Aßs are generated by the proteolytic processing of the amyloid ß-precursor protein (APP). Subsequent cleavage by g-secretase gives rise to Aß (1-40/42) and Aß (11-40/42). Aß (11-40) and Aß (11-42) are major Aß cleavage products generated by BACE.

Detailed Information Datasheet
Storage -20°C
References Liu, K. et al. Biochem. 41, 3128 (2002).
Molecular Weight 3317.9
Sequence
(One-Letter Code)
Pyr-VHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence
(Three-Letter Code)
Pyr - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH
Product Citations Piccini, A. et al. J. Biol. Chem. 280, 34186 (2005).
     
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