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Peptides  >  Amyloid Peptides  >  Beta-Amyloid Peptide Fragments  >>  [Pro18, Asp21]-beta-Amyloid (17-21), iAb5, Human, mouse/rat

Product Name [Pro18, Asp21] - beta - Amyloid (17 - 21), iAb5, Human, mouse/rat
LPFFD
Size 1 mg
Catalog # 60618
US$ $105
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide, derived from the central hydrophobic region of A where valine is replaced by proline, inhibits amyloid formation. Soto, et al. developed this LPFFD sequence for use as a -sheet breaker against A.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Soto, C. et al. Nat. Med. 4, 822 (1998); Sigurdsson, EM. et al. J. Neuropathol. Exp. Neurol. 59, 11 (2000).
Molecular Weight 637.7
Sequence
(One-Letter Code)
LPFFD
Sequence
(Three-Letter Code)
H - Leu - Pro - Phe - Phe - Asp - OH
Product Citations Dukes, KD. et al. (2008). Monitoring the earliest amyloid-beta oligomers via quantized photobleaching of dye-labeled peptides. Anal. Biochem. 382, 29.
     
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