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Peptides  >  Ghrelins and Obestatins  >>  Ghrelin, human

Product Name Ghrelin, human
GS - S(n - octanoyl) - FLSPEHQRVQQRKESKKPPAKLQPR
Size 5 mg
Catalog # AS-24158
US$ $968
Purity % Peak Area By HPLC ≥ 95%
Description

Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.

Detailed Information Datasheet
Storage -20C
References Kojima, M. et al. Nature 402, 656 (1999), doi:10.1038/45230
Yang J., et. al. Cell 132, 387 (2008). doi: 10.1016/j.cell.2008.01.017
Kojima, M. et. al. Physiol Rev 85, 495 (2005), doi: 10.1152/physrev.00012.2004
Perello, M. & Dickson, SL. J Neuroendocrinol 27, 424 (2015), doi: 10.1111/jne.12236
Molecular Weight 3370.9
Sequence
(One-Letter Code)
GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR
Sequence
(Three-Letter Code)
H - Gly - Ser - [Ser(n - octanoyl)] - Phe - Leu - Ser - Pro - Glu - His - Gln - Arg - Val - Gln - Gln - Arg - Lys - Glu - Ser - Lys - Lys - Pro - Pro - Ala - Lys - Leu - Gln - Pro - Arg - OH
Product Citations Mabudi, H. et al. (2011). The effects of ghrelin on ovary histology in Barbus sharpeyi. J Anim Physiol Anim Nutr 10.1111/j.1439-0396.2010.01089.x.
     
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