The cysteine-rich C-terminal domain of AGRP, corresponding to AGRP(87-132), exhibits receptor binding affinity and antagonism equivalent to that of the full-length protein.
Storage
-20°C
References
Ref: Yang, Y. et al. Mol. Endocrinol. 13, 148 (1999); Wilczynski, A. et al. J. Med. Chem. 47, 5662 (2004); Wilczynski, A. et al. J. Med. Chem. 47, 2194 (2004); Millhauser, G. et al. Ann. N. Y. Acad. Sci. 994, 27 (2003).
Molecular Weight
5202.2
Sequence (One-Letter Code)
Ac-CVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT
Sequence (Three-Letter Code)
Ac - Cys - Val - Arg - Leu - His - Glu - Ser - Cys - Leu - Gly - Gln - Gln - Val - Pro - Cys - Cys - Asp - Pro - Cys - Ala - Thr - Cys - Tyr - Cys - Arg - Phe - Phe - Asn - Ala - Phe - Cys - Tyr - Cys - Arg - Lys - Leu - Gly - Thr - Ala - Met - Asn - Pro - Cys - Ser - Arg - Thr - OH.
