Indolicidin, a member of the cathelicidin protein family, is a 13-residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. Indolicidin is microbicidal in-vitro against gram-positive and gram-negative bacteria, fungi, protozoa, and human immunodeficiency virus (HIV-1).
Ref: Ísapay, K. et al. J. Biol. Chem. 275, 12017 (2000); Ahmad, I. et al. Biochim. Biophys. Acta 1237, 109 (1995); Aley, SB. Infect. Immun. 62, 5397 (1994); Robinson, W. et al. J. Leukocyte Biol. 63, 94 (1998).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ile - Leu - Pro - Trp - Lys - Trp - Pro - Trp - Trp - Pro - Trp - Arg - Arg - NH2