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Peptides  >  C3a Peptides  >>  [Trp63, 64]-C3a (63-77)

Product Name [Trp63, 64] - C3a (63 - 77)
WWGKKYRASKLGLAR
Size 1 mg
Catalog # AS-61119
US$ $105
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Proctor LM et al. Intl Immunopharmacol. 9, 800-806 (2009).
2, Ames, R. et al. Immunopharmacol. 38, 87 (1997).
Molecular Weight 1820.2
Sequence
(One-Letter Code)
WWGKKYRASKLGLAR
Sequence
(Three-Letter Code)
H - Trp - Trp - Gly - Lys - Lys - Tyr - Arg - Ala - Ser - Lys - Leu - Gly - Leu - Ala - Arg - OH
Product Citations Russell, J. et al. (2011). Parallel detection of intrinsic fluorescence from peptides and proteins for quantification during mass spectrometric analysis Anal Chem 83 (6) 21872193. doi: 10.1021/ac103023q.
     
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