IRBP, Interphotoreceptor Retinoid Binding Protein Fragment
Size
1 mg
Catalog #
60183-1
US$
$121
Purity
% Peak Area By HPLC ≥ 95%
Description
This 20-residue peptide, a major pathogenic T-cell epitope (161–180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).
Ref: Sonoda, K. et al. J. Immunol. 171, 2652 (2003); Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002); Silver, P. et al. Invest. Ophthal. Vis. Sci. 36, 946 (1995); Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).
Molecular Weight
2209.5
Sequence (One-Letter Code)
SGIPYIISYLHPGNTILHVD
Sequence (Three-Letter Code)
H - Ser - Gly - Ile - Pro - Tyr - Ile - Ile - Ser - Tyr - Leu - His - Pro - Gly - Asn - Thr - Ile - Leu - His - Val - Asp - OH
Datasheet
