Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Signal Transduction Peptides  >>  IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Product Name IRBP, Interphotoreceptor Retinoid Binding Protein Fragment
SGIPYIISYLHPGNTILHVD
Size 1 mg
Catalog # 60183-1
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This 20-residue peptide, a major pathogenic T-cell epitope (161180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).

Detailed Information Datasheet
Storage -20C
References Ref: Sonoda, K. et al. J. Immunol. 171, 2652 (2003); Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002); Silver, P. et al. Invest. Ophthal. Vis. Sci. 36, 946 (1995); Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).
Molecular Weight 2209.5
Sequence
(One-Letter Code)
SGIPYIISYLHPGNTILHVD
Sequence
(Three-Letter Code)
H - Ser - Gly - Ile - Pro - Tyr - Ile - Ile - Ser - Tyr - Leu - His - Pro - Gly - Asn - Thr - Ile - Leu - His - Val - Asp - OH
Product Citations Zhang, Z. et al. (2012). Low dose rapamycin exacerbates autoimmune experimental uveitis. Plos One doi:10.1371/journal.pone.0036589
An, F. et al. Invest Ophthalmol Vis Sci 50, 3778 (2009).
Tan, Jung. et al. J Immunol 178, 5578 (2007).
Pennesi, G. et al. J Clin Invest 111, 1171 (2003).
     
  < Back