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Peptides  >  Thrombin Related Peptides  >>  Thrombin Receptor (42-48) Agonist, human

Product Name Thrombin Receptor (42 - 48) Agonist, human
SFLLRNP
Size 5 mg
Catalog # AS-24170
US$ $171
Purity % Peak Area By HPLC ≥ 95%
Description

This is a thrombin receptor-derived peptide that corresponds to the N-terminal heptapeptide of tethered ligand. It is known to activate thrombin receptor and to stimulate phosphoinositide turnover. The phenylalanine residue at position 2 is known to play a crucial role in activation of the thrombin receptor.

Storage -20C
References 1, Nose T. et al. BBRC, 193(2):694-699 (1993).
2, Molloy, C. et al. J. Clin. Invest. 97, 1173 (1996).
3, Ishida, A. et al. FEBS Lett. 427, 155 (1998).
4, Ishida, A. and H. Fujisawa, J. Biol. Chem. 270, 2163 (1995).
Molecular Weight 846
Sequence
(One-Letter Code)
SFLLRNP
Sequence
(Three-Letter Code)
H - Ser - Phe - Leu - Leu - Arg - Asn - Pro - OH
Product Citations Ludeman, M. et al. (2004). Regulated shedding of PAR1 N-terminal exodomain from endothelial cells. J Biol Chem 279,18592 doi:10.1074/jbc.M310836200
     
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