| Product Name |
Charybdotoxin |
| Size |
1 mg |
| Catalog # |
22428 |
| US$ |
$1045 |
| Molecular Weight |
4296 |
Sequence
(One-Letter Code) |
Pyr-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (Disulfide bridge: 7-28, 13-33 and 17-35) |
Sequence
(Three-Letter Code) |
Pyr - Phe - Thr - Asn - Val - Ser - Cys - Thr - Thr - Ser - Lys - Glu - Cys - Trp - Ser - Val - Cys - Gln - Arg - Leu - His - Asn - Thr - Ser - Arg - Gly - Lys - Cys - Met - Asn - Lys - Lys - Cys - Arg - Cys - Tyr - Ser - OH (Disulfide bridge: 7 - 28, 13 - 33 and 17 - 35) |
| Description |
Charybdotoxin (ChTX) is a Ca2+-activated K+ channel blocker. It depolarizes peripheral T lymphocytes and blocks their mitogen-induced proliferation. ChTX is a highly basic peptide isolated from venom of the scorpion, Leiurus quinquestriatus hebraeus. |
| References |
Ref: Leonard, R. et al. Proc. Natl. Acad. Sci. USA 89, 10094 (1992); Gimenez-Gallego, Proc. Natl. Acad. Sci. USA 85, 3329 (1988). Sugg, E. et al. J. Biol. Chem. 265, 18745 (1990). |
| Storage |
-20°C |
| Detailed Information |
 Product Information
 Material Safety Data Sheets (MSDS)
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| Product Citations |
Bayram, Z. et al. (2010). The role of nitric oxide and potassium channels in the effect of adrenomedullin in human internal thoracic arteries. Regul Pept 161, 92.
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