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Peptides  >  Urotensin related peptides  >>  Urotensin II, human

Product Name Urotensin II, human
ETPDCFWKYCV HCl (Disulfide bridge: 5 - 10)
Size 5 mg
Catalog # AS-27052
US$ $583
Purity % Peak Area By HPLC ≥ 95%
Description

Urotensin II (UII) is a highly potent vasoconstrictor that has been identified as a ligand for the orphan receptor GPR14 which elicits potent vasoconstriction in primates. Intracerebroventricular urotensin II administration produces pressor and tachycardic responses. U-II is localized to the medulla oblongata of the brain and the spinal cord in the central nervous system, but is also found in adrenal glands, kidney and spleen, suggesting neurohormonal or hormonal properties

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Bennett, R. et al. Thorax 9, 401 (2004); Coulouarn, Y. et al. FEBS Lett. 457, 28 (1999); Lin, Y. et al. J. Hypertension 21, 59 (2003); Boucard, A. et al. Biochem. J. 370, 829 (2003) Coulouarn, Y. et al. Proc. Natl. Acad. Sci. USA 95, 15803 (1998).
Molecular Weight 1390.6 36.5
Sequence
(One-Letter Code)
ETPDCFWKYCV HCl (Disulfide bridge: 5-10)
Sequence
(Three-Letter Code)
H - Glu - Thr - Pro - Asp - Cys - Phe - Trp - Lys - Tyr - Cys - Val - OH HCl (Disulfide bridge: 5 - 10)
Product Citations Zheng, J. et al. (2006). Feasibility of supercritical fluid chromatography/mass spectrometry of polypeptides with up to 40-mers. Anal. Chem. 78, 1535.
     
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