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Peptides  >  Luteinizing Hormone-Releasing Hormones and Related Peptides  >>  Luteinizing Hormone-Releasing Hormone (LH-RH), human

Product Name Luteinizing Hormone - Releasing Hormone (LH - RH), human
Pyr - HWSYGLRPG - NH2
Size 25 mg
Catalog # AS-20782
US$ $165
Purity % Peak Area By HPLC ≥ 95%
Description

This decapeptide is a hypothalamic hormone that controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland and promotes mating behavior. It stimulates the secretion of gonadotropins after its interaction with specific G-protein-coupled receptors that are present in plasma membranes of pituitary gonadotrophs. In addition to hypophysiotropic effect, it also plays a autocrine/paracrine role in peripheral organs such as prostate, breast and ovary. Luteinizing hormone-releasing hormone is not only a neurohormone but may also function as a neurotransmitter or neuromodulator.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Kiss, J. and B. Halasz, Neurosci 14, 69 (1985); Zheng, L. et al. Neurosci 46, 407 (1992); Collado, B. et al. Intl J Oncol 24, 725 (2004); Hoffman, G. et al. Brain Res 2005 Aug 5; [Epub ahead of print]; Wang, V. et al. Am J Obstet Gynecol 160, 984 (1989).
Molecular Weight 1182.3
Sequence
(One-Letter Code)
Pyr-HWSYGLRPG-NH2
Sequence
(Three-Letter Code)
Pyr - His - Trp - Ser - Tyr - Gly - Leu - Arg - Pro - Gly - NH2
Product Citations Xu, Y. et al. (2010). Porous Polymer Monolithic Column with Surface-Bound Gold Nanoparticles for the Capture and Separation of Cysteine-Containing Peptides. Anal Chem 82, 3352.
     
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