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Peptides  >  Matrix Metalloproteinases (MMPs)  >>  WAAG-3R, Aggrecanase (ADAM-TS-4) FRET Substrate

Product Name WAAG - 3R, Aggrecanase (ADAM - TS - 4) FRET Substrate
Abz - TEGEARGSVI - Dpa - KK - NH2
Size 1 mg
Catalog # 60431-1
US$ $237
Purity % Peak Area By HPLC ≥ 95%
Description

This FRET peptide was used in an ADAM-TS-4 (Aggrecanase-1) assay. Ex/Em = 340/420 nm.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Zhang, Y. et al. J. Pharmacol. Exp. Ther. 309, 348 (2004).
Molecular Weight 1644.8
Sequence
(One-Letter Code)
Abz-TEGEARGSVI-Dap(Dnp)-KK-NH2
Sequence
(Three-Letter Code)
Abz - Thr - Glu - Gly - Glu - Ala - Arg - Gly - Ser - Val - Ile - Dap(Dnp) - Lys - Lys - NH2
Product Citations Savi, C. et al. (2011). The Design and Synthesis of Novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis. Bioorg Med Chem Lett doi:10.1016/j.bmcl.2011.01.036.
Zhang, Y. et al. J. Pharmacol. Exp. Ther. 309, 348 (2004).
     
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