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Peptides  >  Matrix Metalloproteinases (MMPs)  >>  390 MMP FRET Substrate IV

Product Name 390 MMP FRET Substrate IV
Mca - P - Cha - G - Nva - HA - Dpa - NH2
Size 5 mg
Catalog # AS-27109
US$ $385
Purity % Peak Area By HPLC ≥ 95%
Description

This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.

Detailed Information Datasheet
Storage -20C
References Ref: Lauer-Fields, JL. and GB. Fields, Biol. Chem. 383, 1095 (2002); Lauer-Fields, JL. et al. Biochem. 40, 5795 (2001); Knauper, V. et al. J. Biol. Chem. 271, 1544 (1996).
Molecular Weight 1100.2
Sequence
(One-Letter Code)
Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2
Sequence
(Three-Letter Code)
Mca - Pro - Cha - Gly - Nva - His - Ala - Dap(Dnp) - NH2
     
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