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Peptides  >  NF-kB/Transcription Factors Related Peptides   >>  IKKγ NEMO Binding Domain (NBD) Inhibitory Peptide

Product Name IKKγ NEMO Binding Domain (NBD) Inhibitory Peptide
DRQIKIWFQNRRMKWKKTALDWSWLQTE
Size 1 mg
Catalog # AS-61169
US$ $176
Purity % Peak Area By HPLC ≥ 95%
Description

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.

Detailed Information Datasheet
Storage -20C
References Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003).
Molecular Weight 3693.3
Sequence
(One-Letter Code)
DRQIKIWFQNRRMKWKKTALDWSWLQTE
Sequence
(Three-Letter Code)
H - Asp - Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Thr - Ala - Leu - Asp - Trp - Ser - Trp - Leu - Gln - Thr - Glu - OH
     
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