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Peptides  >  Peptidoglycan Peptides  >>  Ala-γ-D-Glu-DAP

Product Name Ala - γ - D - Glu - DAP
A - (γ - e) - DAP
Size 1 mg
Catalog # AS-60774
US$ $181
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide, with the diaminopimelic acid coupled to the γ-carboxylic acid of the D-isomer of Glu, stimulates Nod1-dependent apoptosis.

Detailed Information Datasheet
Storage -20C
References da Silva Correia, J. et al. Proc. Natl. Acad. Sci. USA 103, 1840 (2006); Baum, EZ. et al. Antimicrobial Agents Chemo. 50, 230 (2006).
Molecular Weight 390.4
Sequence
(One-Letter Code)
A-(γ-e)-DAP
Sequence
(Three-Letter Code)
H - Ala - D - γ - Glu - diaminopimelic acid
Product Citations Seshadri, S. et al. (2009). MAIL regulates human monocyte IL-6 production. J Immunol 183, 5358.
Fukazawa, A. et al. (2008). GEF-H1 mediated control of NOD1 dependent NF-κB activation by Shigella effectors. PLoS Pathog 4, e1000228.
Swaan, PW. et al. (2008). Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2. Am J Respir Cell Mol Biol 39, 536.
da Silva Correia, J. et al. (2007). The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis. J Biol Chem 282, 12557.
da Silva Correia, J. et al. (2007). SGT1 is essential for Nod1activation Proc Natl Acad Sci 104, 6764.
     
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