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Peptides  >  Prion Protein (PrP) Fragments  >>  PrP (106-126)

Product Name PrP (106 - 126)
Size 1 mg
Catalog # 61160
US$ $176
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106–126) stimulates leucocyte migration in a dose-dependent manner.

Detailed Information Datasheet
Storage -20°C
References Ref: Diomede, L. et al. Biochem. J. 320, 563 (1996); Florio, T. et al. J. Neurosci. Res. 54, 341 (1998).
Molecular Weight 1912.3
Sequence
(One-Letter Code)
KTNMKHMAGAAAAGAVVGGLG
Sequence
(Three-Letter Code)
H - Lys - Thr - Asn - Met - Lys - His - Met - Ala - Gly - Ala - Ala - Ala - Ala - Gly - Ala - Val - Val - Gly - Gly - Leu - Gly - OH
     
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