Acetyl - Calpastatin (184 - 210), CS peptide, human
Size
0.5 mg
Catalog #
60842
US$
$115
Purity
% Peak Area By HPLC ≥ 95%
Description
Calpastatin is a widely distributed endogenous inhibitor protein specifically acting on calpain (Ca2+-dependent cysteine endopeptidase). This 27-residue peptide encoded by Exon 1B, including a 12-residue middle conserved sequence, shows strong inhibition against calpain I (low Ca2+-requiring form), and calpain II (high Ca2+-requiring form), but not against papain or trypsin.
Ref: Maki, M. et al. J. Biol. Chem. 264, 18866 (1989); Betts, R. et al. J. Biol. Chem. 278, 7800 (2003); Eto, A. et al. J. Biol. Chem. 270, 25115 (1995).
Molecular Weight
3177.6
Sequence (One-Letter Code)
Ac-DPMSSTYIEELGKREVTIPPKYRELLA-NH2
Sequence (Three-Letter Code)
Ac - Asp - Pro - Met - Ser - Ser - Thr - Tyr - Ile - Glu - Glu - Leu - Gly - Lys - Arg - Glu - Val - Thr - Ile - Pro - Pro - Lys - Tyr - Arg - Glu - Leu - Leu - Ala - NH2
Poster
