| Product Name |
Keratin K18 - C |
| Size |
5 mg |
| Catalog # |
60214-5 |
| US$ |
$485 |
| Molecular Weight |
1418.5 |
Sequence
(One-Letter Code) |
RPVSSAApSVYAGAC |
Sequence
(Three-Letter Code) |
H - Arg - Pro - Val - Ser - Ser - Ala - Ala - pSer - Val - Tyr - Ala - Gly - Ala - Cys - OH |
| Description |
This peptide corresponds to human keratin K18 amino acids 26-38, with an additional C-terminal cysteine. The sequence is identical to mouse K18 except that human K18 Val28 is replaced by alanine in the mouse sequence. Members of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in-vivo, in a cell-cycle- and phosphorylation-dependent manner. K18 Ser33 phosphorylation is essential for the association of K18 with 14-3-3 proteins and plays a role in keratin organization and distribution. |
| References |
Ref: Ku, NO. et al. EMBO J. 17, 1892 (1998). |
| Storage |
-20°C |
| Detailed Information |
 Material Safety Data Sheets (MSDS)
|
| Product Citations |
Dayon, Löıc. et al. J. Mass. Spectrom. 41, 1484 (2006).
|
