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Peptides  >  Cancer Research Peptides  >>  PRAME epitope (PRA300-309) Tumor-associated antigen

Product Name PRAME epitope (PRA300 - 309) Tumor - associated antigen
ALYVDSLFFL
Size 1 mg
Catalog # 60594-1
US$ $137
Purity % Peak Area By HPLC ≥ 95%
Description

PRAME (Preferentially Expressed Antigen of Melanoma), first isolated as a human melanoma antigen recognized by cytotoxic T cells (CTL), is frequently expressed in a variety of cancers. The PRAME gene can be detected in some of the hematological malignancies, neuroblastomas and normal testis. PRAME is a promising marker for detection of minimal residual disease (MRD) in patients with leukemia and a particularly attractive target for immunotherapeutic strategies in neuroblastoma.

Storage -20C
References Ref: Matsushita, M. et al. Leuk. Lymphoma 44, 439 (2003); Kessler, J. et al. J. Exp. Med. 193, 73 (2001).
Molecular Weight 1187.4
Sequence
(One-Letter Code)
ALYVDSLFFL
Sequence
(Three-Letter Code)
H - Ala - Leu - Tyr - Val - Asp - Ser - Leu - Phe - Phe - Leu - OH
     
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