Cocaine- and amphetamine-regulated transcript (CART) peptides (55 to 102 and 62 to 102) are neurotransmitters with important roles in a number of physiologic processes. CART 55 to 102 blunts some of the behavioral effects of cocaine and dopamine (DA). Infusion of CART (55-102) affects body weight homeostasis in rats. CART also produces anxiety-like behavior in rodents.
Storage
-20°C
References
Ref: Kuhar, M. et al. AAPS J. 7, 25 (2005) Rohner, F. et al. Int. J. Obes. Relat. Metab. Disord. 26, 143 (2002); Chaki, S. et al. Eur. J. Pharmacol. 464, 49 (2003).
Molecular Weight
5259.3
Sequence (One-Letter Code)
IPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLKCL (Disulfide bridge: 74-94, 68-86, and 88-101)
Sequence (Three-Letter Code)
H - Ile - Pro - Ile - Tyr - Glu - Lys - Lys - Tyr - Gly - Gln - Val - Pro - Met - Cys - Asp - Ala - Gly - Glu - Gln - Cys - Ala - Val - Arg - Lys - Gly - Ala - Arg - Ile - Gly - Lys - Leu - Cys - Asp - Cys - Pro - Arg - Gly - Thr - Ser - Cys - Asn - Ser - Phe - Leu - Leu - Lys - Cys - Leu - OH (Disulfide bridge: 74 - 94, 68 - 86, and 88 - 101)
