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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  TAT (47-57)

Product Name TAT (47 - 57)
YGRKKRRQRRR
Size 1 mg
Catalog # 60023-1
US$ $93
Description

This is the most characterized fragment of the HIV transactivator protein (TAT). This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis.

Detailed Information Datasheet
Storage -20C
References Ref: Wang, H. et al. J. Clin. Invest. 109, 1463 (2002); Ziegler et al. Biochem. 44, 138 (2005); Wender, PA. et al. Proc. Natl. Acad. Sci. USA 97, 13003 (2000).
Molecular Weight 1559.9
Sequence
(One-Letter Code)
YGRKKRRQRRR
Sequence
(Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - OH
Product Citations Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J 10.1042/BJ20101021.
Wang, G. et al. (2010). Resolving rotational motions of nano-objects in engineered environments and live cells with gold nanorods and differential interference contrast microscopy. J Am Chem Soc 132, 16417.
Chothe, P. et al. (2009). Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells. Invest Opthalmol Visual Sci 51, 413.
Sun, W. et al. (2009). Wavelength-dependent differential interference contrast microscopy: selectively imaging nanoparticle probes in live cell. Anal Chem 81, 9203.
Jain, M. et al. (2005). Penetratin improves tumor retention of single-chain antibodies: A novel step toward optimization of radioimmunotherapy of solid tumors 65, 7840.
Matsushita, K. et al. (2005). A novel class of fusion polypeptides inhibits exocytosis. Mol Pharmacol 67, 1137.
     
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