The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.
Storage
-20°C
References
Ref: Curnis, F. et al. Cancer Res. 62, 867 (2002); Curnis, F. et al. J. Clin. Invest. 110, 475 (2002).