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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  Aminopeptidase N Ligand (CD13), NGR peptide

Product Name Aminopeptidase N Ligand (CD13), NGR peptide
CNGRCG (Disulfide bridge: 1 - 5)
Size 5 mg
Catalog # AS-60171-5
US$ $484
Description

The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.

Storage -20C
References Ref: Curnis, F. et al. Cancer Res. 62, 867 (2002); Curnis, F. et al. J. Clin. Invest. 110, 475 (2002).
Molecular Weight 606.7
Sequence
(One-Letter Code)
CNGRCG (Disulfide bridge: 1-5)
Sequence
(Three-Letter Code)
H - Cys - Asn - Gly - Arg - Cys - Gly - OH (Disulfide bridge: 1 - 5)
Product Citations Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J doi:10.1042/BJ20101021.
     
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