Insulin secretory rate can be estimated from peripheral C-peptide concentrations in dogs. Plasma C-peptide concentrations during glucagon stimulation testing is variable in diabetic dogs and may represent dogs with type-1 and type-2 diabetes or more likely, differences in severity of β-cell loss in dogs with type-1 diabetes.
Ref: Montgomery, T. et al. J. Vet. Intern. Med. 10, 116(1996); Polonsky, K. et al. J. Clin. Invest. 74, 1821 (1984).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Glu - Val - Glu - Asp - Leu - Gln - Val - Arg - Asp - Val - Glu - Leu - Ala - Gly - Ala - Pro - Gly - Glu - Gly - Gly - Leu - Gln - Pro - Leu - Ala - Leu - Glu - Gly - Ala - Leu - Gln - OH