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Peptides  >  Cytochromes and Related Peptides  >>  MCC (88-103)

Product Name MCC (88 - 103)
Size 1 mg
Catalog # AS-60204-1
US$ $99
Purity % Peak Area By HPLC ≥ 95%

This peptide is derived from the carboxyl terminus of moth MCC (88V103) and pigeon cytochrome c plays a major role in T-cell selection. MCC (88-103) can induce positive selection of TCR transgenic thymocytes

Storage -20C
References Ref: Garcia, G. et al. J. Immunol. 166, 3151 (2001); Wang, R. et al. Proc. Natl. Acad. Sci. USA 95, 3804 (1998).
Molecular Weight 1805.1
(One-Letter Code)
(Three-Letter Code)
H - Ala - Asn - Glu - Arg - Ala - Asp - Leu - Ile - Ala - Tyr - Leu - Lys - Gln - Ala - Thr - Lys - OH
Product Citations Fazilleau, N. et al. (2009). The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nature Immunol 10, 375. doi:10.1038/ni.1704.
Sojka, DK. et al. (2004). IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition. J Immunol 172, 6136. doi: 10.4049/​jimmunol.172.10.6136.
Malherbe, L. et al. (2004). Clonal selection of Helper T Cells is determined by an affinity threshold with no further skewing of TCR binding properties. Immunity. 21, 669. doi: http://dx.doi.org/10.1016/j.immuni.2004.09.008.
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