Ghrelin, rat, mouse GS - S(n - octanoyl) - FLSPEHQKAQQRKESKKPPAKLQPR
% Peak Area By HPLC ≥ 95%
Rat/mouse Ghrelin differs from human Ghrelin on the 11th and 12th position - RV (Arg-Val) in rat/mouse and KA (Lys-Ala) in human. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.