This is a fragment of nonstructural protein 2 (NS2) residues 114 to 121 of murine H-2 Db- and Kb-restricted immunogenic CTL epitope of influenza PR8 virus. Antigen-specific recognition of peptides bound to major histocompatibility complex class I molecules is mediated by CD8+ T lymphocytes. CD8+ cytotoxic T lymphocyte (CTL) responses play a central role in protective immunity against viral and intracellular bacterial infections.
Ref: Zhong, W. et al. J. Biol. Chem 278, 45135 (2003); Andreansky, S. et al. Journal of Virology, 79, 4329 (2005); Mansour Haeryfar. S. et al. The Journal of Immunology 174, 3344 (2005)
Molecular Weight
1011.2
Sequence (One-Letter Code)
RTFSFQLI
Sequence (Three-Letter Code)
H - Arg - Thr - Phe - Ser - Phe - Gln - Leu - Ile - OH