This is a reverse transcriptase (RT) epitope (Pol residues 476-484). Within HIV-1 RT the peptide appears to be the dominant HLA A*0201-restricted epitope. Was used to investigate possible mechanisms behind HIV-1 escape from CTL. IV9 is the actual epitope processed and presented in HIV-1-infected cell lines
Ref: Sewell, A. et al. The Journal of Immunology 162, 7075 (1999); Jamieson, B. et al. The Journal of Immunology 171, 5372 (2003); Ref: Brander, C. et al. J. Clin. Invest 101, 2559 (1998); Goulder,P. et al. J. Exp. Med 185, 1423 (1997)
Molecular Weight
991.2
Sequence (One-Letter Code)
ILKEPVHGV
Sequence (Three-Letter Code)
H - Ile - Leu - Lys - Glu - Pro - Val - His - Gly - Val - OH
Material Safety Data Sheets (MSDS)
