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Peptides  >  Amyloid Peptides  >  Beta-Amyloid Peptide Fragments  >>  Beta-Amyloid (25-35), Human, mouse/rat

Product Name Beta - Amyloid (25 - 35), Human, mouse/rat
GSNKGAIIGLM
Size 1 mg
Catalog # 24227
US$ $49
Purity % Peak Area By HPLC ≥ 95%
Description

A (25-35) is the main factor responsible for A neurotoxic effects.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Carvalho, K. et al. Braz. J. Med. Biol. Res. 3, 1153 (1997).
Molecular Weight 1060.3
Sequence
(One-Letter Code)
GSNKGAIIGLM
Sequence
(Three-Letter Code)
H - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - OH
Product Citations Qu, J. et al. (2011) S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide. PNAS 108, 14330 (2011). doi: 10.1073/pnas.1105172108
Morte, B. et al. (2011). Monocyte-mediated regulation of genes by the amyloid and prion peptides in SH-SY5Y neuroblastoma cells. Neurochem Int doi:10.1016/j.neuint.2011.01.019.
Ravindran, C. et al. (2010). CpG-ODNs induces up-regulated expression of chemokine CCL9 in mouse macrophages and microglia. Cell Immunol 260, 113.
Huang, W-C. et al. (2009). Enlargement of Aβ aggregates through chemokine-dependent microglial clustering. Neurosci Res 63, 280.
Wang, H.Y. et al. (2009). Dissociating β-Amyloid from {alpha}7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes {alpha}7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain. J Neuro 10, 10961.
Seyb, KI. et al. (2008). Identification of Small Molecule Inhibitors of β-Amyloid Cytotoxicity through a Cell-Based High-Throughput Screening Platform. J Biomol Screen 13, 870.
Sun, K. et al. (2008). Novel Genetic Tools Reveal Cdk5s Major Role in Golgi Fragmentation in Alzheimers Disease. Mol Biol Cell 19, 3052.
Tateno, M. et al. (2008). Neuroprotective effects of Yi-Gan San against beta amyloid-induced cytotoxicity on rat cortical neurons. Pro Neuro-Pyschopharmacol Biol Pysch 32, 1704.
Hashioka, S. et al. (2007). Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation. Free Radical Bio Med 42, 945.
Martnez, T. and A. Pascual (2007). Gene expression profile in β-amyloid-treated SH-SY5Y neuroblastoma cells. Brain Res Bull 72, 225.
Nelson, TJ. and DL. Alkon (2007). Protection against β-Amyloid-induced Apoptosis by Peptides Interacting with β-Amyloid. J Biol Chem 282, 31238.
Pu, F. et al. (2005). Differential effects of buckwheat and kudingcha extract on neuronal damage in cultured hippocampal neurons and spatial memory impairment induced by scopolamine in an eight-arm radial maze. J Health Sci 51, 636.
Egashira, N. et al. (2002). Hypoxia enhances β-amyloid-induced apoptosis in rat cultured hippocampal neurons. Japanese J Pharmacol 90, 321.
Kawahara, M. and Y. Kuroda (2001). Intracellular Calcium Changes in Neuronal Cells Induced by Alzheimer's -Amyloid Protein Are Blocked by Estradiol and Cholesterol. Cell Mol Neurobio 21, 1.
Yatin, SM. et al. (1998). Temporal relations among amyloid β-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses. J Mol Neurosci 11, 183.
Yatin, S. et al. (1999). Alzheimer's amyloid β-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity: protective effect of vitamin E. Neurosci Lett 263, 17.
     
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