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Peptides  >  Kinases/Phosphatase Substrates  >  AKT/PKB/Rac-protein kinases  >>  Crosstide [GRPRTSSFAEG]

Product Name Crosstide [GRPRTSSFAEG]
GRPRTSSFAEG
Size 5 mg
Catalog # AS-60209-5
US$ $281
Purity % Peak Area By HPLC ≥ 95%
Description

Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB. It displays similar specificities towards PKBα, PKBβ and PKBγ isoforms. It is also recognized by MAPKAP kinase-1 and p70S6K. The fluorescent and biotinlyated peptides demonstrate similar enzyme activities.

Detailed Information Datasheet
Storage -20C
References Ref: Dai, F. et al. Biochem. Biophys. Res. Commun. 293, 1191 (2002). Meier, R. et al. J. Biol. Chem. 272, 30491 (1997); Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).
Molecular Weight 1164.2
Sequence
(One-Letter Code)
GRPRTSSFAEG
Sequence
(Three-Letter Code)
H - Gly - Arg - Pro - Arg - Thr - Ser - Ser - Phe - Ala - Glu - Gly - OH
Product Citations Okamura, T. et al. (2009). Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor.J. Biol. Chem. 284, 16979.
     
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