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Fluorescent Dyes  >  Enzyme Detection Reagents  >>  NFF-2

Product Name NFF - 2
Mca - RPKPYA - Nva - WM - K(Dnp) - NH2
Size 5 mg
Catalog # 27111
US$ $385
Purity % Peak Area By HPLC ≥ 95%
Description

NFF-2 is hydrolyzed 60 times more rapidly by MMP-3 (kcat/Km = 59,400 s-1 M-1) than MMP-1. However, it has little discrimination between MMP-3, MMP-2 (kcat/Km = 54,000 s-1 M-1), and MMP-9 (kcat/Km = 55,300 s-1 M-1). The substrate can also be cleaved by MMP-8 and 12. Abs/Em = 325/393 nm.

Storage -20C
References Ref: Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002); Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994).
Molecular Weight 1656.2
Sequence
(One-Letter Code)
Mca-RPKPYA-Nva-WM-K(Dnp)-NH2
Sequence
(Three-Letter Code)
Mca - Arg - Pro - Lys - Pro - Tyr - Ala - Nva - Trp - Met - Lys(Dnp) - NH2
Product Citations Kadonosono, T. et al. Appl. Microbio. Biotech. 75, 1285 (2007).
     
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