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Peptides  >  Cancer Research Peptides  >>  G209-2M, gp100 (209-217)

Product Name G209 - 2M, gp100 (209 - 217)
IMDQVPFSV
Size 1 mg
Catalog # AS-61277
US$ $110
Purity % Peak Area By HPLC ≥ 95%
Description

This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigene. It can be processed, presented, and recognized by T cells. Alteration of the G209 peptide to G209-2M at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100

Storage -20C
References Schaed, S. et al. Clin. Canc. Res. 8, 967 (2002); Paczesny, S. et al. JEM 199, 1503 (2004).
Molecular Weight 1035.2
Sequence
(One-Letter Code)
IMDQVPFSV
Sequence
(Three-Letter Code)
H - Ile - Met - Asp - Gln - Val - Pro - Phe - Ser - Val - OH
     
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