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| Product Name |
JAG - 1 (188 - 204), Jagged - 1 (188 - 204), Notch Ligand, DSL Peptide |
| Size |
1 mg |
| Catalog # |
61298 |
| US$ |
$155 |
| Molecular Weight |
2107.4 |
Sequence
(One-Letter Code) |
CDDYYYGFGCNKFCRPR |
Sequence
(Three-Letter Code) |
H - Cys - Asp - Asp - Tyr - Tyr - Tyr - Gly - Phe - Gly - Cys - Asn - Lys - Phe - Cys - Arg - Pro - Arg - OH |
| Description |
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-?B activation. |
| References |
Nickoloff, B. et al. Cell Death Different. 9, 842 (2002). |
| Storage |
-20°C |
| Detailed Information |
 Product Information
 Material Safety Data Sheets (MSDS)
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| Product Citations |
Ma, X-B. et al. (2009). Expression and role of Notch signalling in the regeneration of rat tracheal epithelium. Cell Proliferation 42, 15.
Sainson, R.C.A. et al (2005). Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB Journal 19, 1027.
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