Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Melan-A and Mucin Related Peptides  >>  MUC3

Product Name MUC3
HSTPSFTSSITTTETTS
Size 1 mg
Catalog # 61338
US$ $105
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is derived from the tandem repeat of Muc 3 mucin protein. MUC3 is a membrane associated mucin of the small intestine. Probiotic microbes induce MUC3 mucin transcription and translation with extracellular secretion of the MUC3 mucins. Mucins are highly O-glycosylated proteins which polymerize through the formation of disulfide bonds to form a gel that is secreted onto the surface of glandular epithelia. Mucins play a protective role for the adjoining epithelial tissues under normal physiological conditions; whereas an altered expression of mucins is often associated with carcinomas and neoplastic lesions.

Storage -20C
References Lesuffleur, T. et al. J. Biol. Chem. 270, 13665 (1995); Singh, A. et al. Cancer Res. 64, 622 (2004); Mack, D. et al. Gut 52, 827(2003).
Molecular Weight 1784.9
Sequence
(One-Letter Code)
HSTPSFTSSITTTETTS
Sequence
(Three-Letter Code)
H - His - Ser - Thr - Pro - Ser - Phe - Thr - Ser - Ser - Ile - Thr - Thr - Thr - Glu - Thr - Thr - Ser - OH
Product Citations Liu, F. et a. (2010). Porcine Small Intestinal Epithelial Cell Line (IPEC-J2) of Rotavirus Infection As a New Model for the Study of Innate Immune Responses to Rotaviruses and Probiotics. Viral Immunol 23, 135.
     
  < Back