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Peptides  >  Melan-A and Mucin Related Peptides  >>  MUC3

Product Name MUC3
Size 1 mg
Catalog # 61338
US$ $105
Purity % Peak Area By HPLC ≥ 95%

This peptide is derived from the tandem repeat of Muc 3 mucin protein. MUC3 is a membrane associated mucin of the small intestine. Probiotic microbes induce MUC3 mucin transcription and translation with extracellular secretion of the MUC3 mucins. Mucins are highly O-glycosylated proteins which polymerize through the formation of disulfide bonds to form a gel that is secreted onto the surface of glandular epithelia. Mucins play a protective role for the adjoining epithelial tissues under normal physiological conditions; whereas an altered expression of mucins is often associated with carcinomas and neoplastic lesions.

Storage -20C
References Lesuffleur, T. et al. J. Biol. Chem. 270, 13665 (1995); Singh, A. et al. Cancer Res. 64, 622 (2004); Mack, D. et al. Gut 52, 827(2003).
Molecular Weight 1784.9
(One-Letter Code)
(Three-Letter Code)
H - His - Ser - Thr - Pro - Ser - Phe - Thr - Ser - Ser - Ile - Thr - Thr - Thr - Glu - Thr - Thr - Ser - OH
Product Citations Liu, F. et a. (2010). Porcine Small Intestinal Epithelial Cell Line (IPEC-J2) of Rotavirus Infection As a New Model for the Study of Innate Immune Responses to Rotaviruses and Probiotics. Viral Immunol 23, 135.
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