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Peptides  >  Amyloid Peptides  >  Beta-Amyloid Peptide Fragments  >>  [Ac-Lys(Me)16, N-Me-Val18]-beta-Amyloid (16-20)-NH2, Human, mouse/rat

Product Name [Ac - Lys(Me)16, N - Me - Val18] - beta - Amyloid (16 - 20) - NH2, Human, mouse/rat
Ac - K(Me) - L - (N - Me - V) - FF - NH2
Size 1 mg
Catalog # AS-61344
US$ $132
Purity % Peak Area By HPLC ≥ 95%
Description

This membrane permeable N-methyl amino acid-containing peptide inhibits b-amyloid 1 to 40 fibrillogenesis. Its structure is remarkably stable to changes in solvent conditions and resists denaturation by heating, changes in pH (from 2.5 to 10.5), and addition of denaturants such as urea and guanindine-HCl. The striking water solubility, in combination with the hydrophobic composition of the peptide, allows the peptide to pass spontaneously through cell membranes.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Gordon, D. et al. J. Pept. Res. 60, 37 (2002).
Molecular Weight 721.9
Sequence
(One-Letter Code)
Ac-K(Me)-L-(N-Me-V)-FF-NH2
Sequence
(Three-Letter Code)
Ac - Lys(Me) - Leu - (N - Me - Val) - Phe - Phe - NH2
     
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