in vitro.; RRRRRRRRGEDIIRNIARHLAQVGDSMDR; H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH">

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Bid BH3-R8

Product Name	Bid BH3 - R8
Size	1 mg
Catalog #	62057
US$	$231
Purity	% Peak Area By HPLC ≥ 95%
Description	Bid BH3 is a pro-apoptotic member of the "BH3-only" subset of BCL-2 family proteins that constitute a critical control point in apoptosis. BID BH3 interacts with Bax to induce mitochondrial outer membrane permeabilization in the apoptotic process. This peptide contains 8 Arg residues in the L-isomeric form on the N-terminus. BID Tagging with poly-arginine facilitates cell internalization. R8BIDH3 has been shown to induce apoptosis of Jurkat leukemia cells in vitro.
Storage	-20°C
References	Letai, A. J Clin Invest 115, 2648 (2005). Goldsmith, K. et al. Proc Amer Assoc Cancer Res 45,1829 (2004). Goldsmith, K. et al. Oncogene 25, 4525 (2006).
Molecular Weight	3616.2
Sequence (One-Letter Code)	RRRRRRRRGEDIIRNIARHLAQVGDSMDR
Sequence (Three-Letter Code)	H - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Gly - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg - OH

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