Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  MAPS Peptides  >>  MAPS, Core, 8-Branch

Product Name MAPS, Core, 8 - Branch
K4K2KA - NH2
Size 10 mg
Catalog # AS-21006
US$ $242
Purity % Peak Area By HPLC ≥ 95%
Description

Multiple Antigenic Peptides (MAPs) are peptides that are branched artificially, in which Lys residues are used as the scaffolding core to support the formation of ≤8 branches with varying or the same peptide sequences. It is a method for producing high-titre peptide antibodies and synthetic peptide vaccines. This system utilizes the alpha- and epsilon-amino functional groups of lysine to form a backbone to which multiple peptide chains are attached. Depending on the number of lysine tiers (2, 4, 8, etc.), different numbers of peptide branches can be synthesized. This technology enables successful production of high-titre antibodies. MAPs have a high molar ratio of the peptide antigen to the core molecule, and no carrier protein is needed to elicit an antibody response.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Wang CY. et al. Science 254:285-288 (1991)
2, Posnett D. et al. J Biol. Chem. 263:1719-1725 (1988)
3, Tam JP. PNAS USA, 85:5409-5413 (1988)
4, Kowasczyk W. et al. J Pept Sci, 17(4):247-251 (2011).
Molecular Weight 985.3
Sequence
(One-Letter Code)
K4K2KA-NH2
Sequence
(Three-Letter Code)
H - (Lys)4 - (Lys)2 - Lys - Ala - NH2
Product Citations Abboud, N. et al. (2009). Interplay between Akt and p38 MAPK Pathways in the Regulation of Renal Tubular Cell Apoptosis Associated with Diabetic Nephropathy. J Biol Chem 284, 25077.
     
  < Back