Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Cell Adhesion Peptides  >>  Bacterial Sortase Substrate I, FRET

Product Name Bacterial Sortase Substrate I, FRET
DABCYL - LPETG - EDANS
Size 1 mg
Catalog # AS-62231
US$ $237
Purity % Peak Area By HPLC ≥ 95%
Description

This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.

Detailed Information Datasheet
Storage -20C
References Mazmanian, S. et al. PNAS 99, 2293 (2002); Ilangovan, U. et al. PNAS 98, 6056 (2001), Ton-That, H. et al. PNAS 96, 12424 (1999); W. Navarre and O. Schneewind Microbiol. Mol. Biol. Rev. 63, 174 (1999).
Molecular Weight 1015.2
Sequence
(One-Letter Code)
DABCYL-LPETG-EDANS
Sequence
(Three-Letter Code)
DABCYL - Leu - Pro - Glu - Thr - Gly - EDANS
     
  < Back