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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  Tat-C (48-57)

Product Name Tat - C (48 - 57)
CGRKKRRQRRR
Size 1 mg
Catalog # AS-62063
US$ $66
Description

This peptide is amino acids 48 to 57 fragment of TAT with an additional cysteine residue at the N-terminus. This peptide contains the protein transduction domain (PTD) of the HIV Tat protein that inhibits HSV-1 entry. The addition of a cysteine residue to the N-terminus of the Tat-PTD (Tat-C peptide) improves the antiviral activity against HSV-1 and HSV-2. Tat-C acts extracellularly, blocking entry of adsorbed virus immediately without eluting virions.

Detailed Information Datasheet
Storage -20C
References Bultmann, H. et al. Antimicrob. Agents Chemother. 51, 1596 (2007).
Molecular Weight 1499.8
Sequence
(One-Letter Code)
CGRKKRRQRRR
Sequence
(Three-Letter Code)
H - Cys - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - OH
Product Citations Xiong, X. et al. (2010). Virus-mimetic polymeric micelles for targeted siRNA delivery. Biomater 31, 5886.
     
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