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Peptides  >  Renin  >>  Renin 390 FRET Substrate I

Product Name Renin 390 FRET Substrate I
R - E(EDANS) - IHPFHLVIHT - K(DABCYL) - R
Size 1 mg
Catalog # AS-62022
US$ $215
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a renin substrate (angiotensinogen) labeled with EDANS/ DABCYL FRET pair for renin activity studies. The renin-angiotensin system (RAS), acting through type 1 angiotensin (AT1) receptors, is a master regulator of fluid homeostasis.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Crowley, S. et al. J. Clin. Invest. 115, 1092 (2005); Holzman, T. et al. J. Protein Chem. 9, 663 (1990).
Molecular Weight 2282.7
Sequence
(One-Letter Code)
R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Sequence
(Three-Letter Code)
H - Arg - Glu(EDANS) - Ile - His - Pro - Phe - His - Leu - Val - Ile - His - Thr - Lys(DABCYL) - Arg - OH
Product Citations Hanner, F. et al. (2008). Increased renal renin content in mice lacking the Na+:H+ exchanger NHE2. Am J Physiol Renal Physiol doi:10.1152/ajprenal.00591.2007
Toma, I. et al. (2006). Imaging renin content and release in the living didney. Nephron Physiol 103, 71.
     
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