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Assay Kits  >  Cathepsin Assay Kits  >>  SensoLyte® 440 Cathepsin S Assay Kit *Fluorimetric*

Product Name SensoLyte® 440 Cathepsin S Assay Kit *Fluorimetric*
Size 1 kit
Catalog # 72100
US$ $374
Description

Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.

The SensoLyte® 440 Cathepsin S Assay Kit uses a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin S cleavage, and which can be detected with excitation at 354 nm and emission at 442 nm.

The kit contains:
• AMC based fluorogenic substrate (Ex/Em=354 nm/442 nm upon cleavage)
• Assay buffer
• Human spleen Cathepsin S
• Inhibitor
• Fluorescence reference standard for calibration
• A detailed protocol

Kit size: 100 assays (96-well plate)

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
     
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